Wednesday 12 September 2018
10.15 – 12.45
Innovation Forums
Medicinal chemistry
The perpetual task of Medicinal Chemistry and Drug Discovery is the finding and profiling of pharmacologically active and safe medicine.
In this forum the importance of new methodologies for profiling and synthesis of new compounds will be presented and discussed including new computational approaches for compound design.
Chairs:
Daniel Gygax (FHNW, Muttenz, Switzerland)
Gerhard Grundler (FHNW, Muttenz, Switzerland)
10.15
Fishing for compound targets using CRISPR-mediated bar-coded deletion collections
D. Estoppey1, C.M. Lee2, M. Janoschke3, M. Spiess3, G. Bonamy2, D. Hoepfner1
1Chemical Biology & Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland, 2Novartis Institutes for Tropical Diseases, Singapore, Singapore, 3Biozentrum der Universität Basel, Basel, Switzerland
10.45
Phage display selection of chemically cyclized peptides for the development of therapeutics
C. Heinis
Institute of Chemical Sciences and Engineering, EPFL, Lausanne, Switzerland
11.45
The Screening Compound Collection: a key asset for drug discovery
C. Boss
DD Chemistry Oncology, Idorsia Pharmaceuticals Ltd, Allschwil / BL, Switzerland
12.15
Can a computer design a drug?
J.G. Cumming
F. Hoffmann-La Roche, Basel, Switzerland
Shanghai 1