BASEL LIFE 2019

9–12 September 2019

Congress Center Basel
Switzerland

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Poster Numbers

Poster Number Postertitle Firstname Lastname
P01 A simple and flexible computational framework for inferring sources of heterogeneity from single-cell dynamics Lekshmi Dharmarajan
P02 Deciphering the role of Nrf2-related glutathione pathways in malignant cancer cells Agathe Morand
P03 Realizing Waddington's metaphor: Inferring regulatory landscapes from single-cell gene expression data Jeremie Breda
P04 MDR to preXDR to XDR tuberculosis: whole genome sequencing reveals several different evolutionary strategies Serej Ley
P05 Representation learning of disease associated cell subsets from single-cell RNA sequencing data Nicolas Ochsner
P06 HABP4 is required for colon tumorigenesis in the murine colitis-associated carcinoma model Talita Diniz Melo Hanchuk
P07 The challenges of annotation and integration of scRNA-Seq into Bgee Sara Fonseca Costa
P08 Discovery of potent anthranilic acid derivatives for the treatment of chronic inflammation Madhwi Ojha
P09 An alignment-free method for predicting phenotypes of sequenced bacterial isolates Maido Remm
P10 Gut microbiota, neuropsychometric test scores and neuroimaging differentiate cognitive impairment in Parkinson's disease Suleyman Yildirim
P11 Leveraging correlated risks to increase power in Genome-Wide Association Studies Ninon Mounier
P12 Non-parametric modeling of state shifts in microbial communities Ville Laitinen
P13 Insights into lung microbiome dysbiosis in patients with active pulmonary tuberculosis: a nested case-control study Monica R. Ticlla
P14 Codon bias in lincRNAs: a mechanism to prevent translation? Anneke Brümmer
P15 Tracking bacterial pathogens in the regime of fast horizontal gene transfer Nicholas Noll
P16 Deep motif deconvolution of HLA-II peptidomes for robust class II epitope predictions Julien Racle
P17 Condition-specific series of metabolic sub-networks and its application for gene set enrichment analysis Van Du T. Tran
P18 Characterisation of wild-type Von Hippel-Lindau ccRCC with the application of both a bottom-up and a top-down multi-omic integrative approach Aashil A Batavia
P19 PCTAIRE1 kinase overcomes PolST induced mitotic arrest and cell death Qaaifah Gillani
P20 Cracking the HCC code - a multi-OMICS study of liver cancer to understand its development and therapy response Eva Dazert
P21 shortRNA: a flexible framework for the analysis of short RNA sequencing data Deepak K Tanwar
P22 Explore a new ligand binding site of G protein-coupled receptors Shuguang Yuan
P23 A national infrastructure network to enable secure biomedical data processing: the BioMedIT project Martin Fox
P24 A bioinformatic workflow to enable species assignment directly from metagenetic sequencing Tsering Wüthrich
P25 SwissTargetPrediction: web tool update and large-scale evaluation of protein target prediction for bioactive small molecules Antoine Daina
P26 LEMMI: a live evaluation of computational methods for metagenome investigation Mathieu Seppey
P27 Microbial population in fluctuating environments, how the size influences the strategy Athos Fiori
P28 Molecular and functional characterization of papillary renal cell carcinoma Silvia Angori
P29 Characterization of kinase activities inferred by phosphoproteomics in myeloid cell lines treated with targeting compounds for the identification of driving and bypassing oncogenic signaling pathways Mahmoud Hallal
P30 Loss of hexokinase 2 causes insulin resistance Mitsugu Shimobayashi
P31 Arsenic disturbs the gut microbiome of a disadvantaged community in Nepal Samendra Sherchan
P32 Are metagenomic data sufficiently informative to robustly predict inflammatory bowel disease status? Lusine Khachatryan
P33 Cluster partitions and fitness landscapes of the Drosophila fly microbiome Lisa Lamberti
P34 Copy number phylogenetics for single cells Mustafa Anil Tuncel
P35 A single cell lineage tree reconstruction algorithm based on an adjusted Steiner tree approximation algorithm Mohammad Hadi Foroughmand Araabi
P36 Machine learning-aided single-cell transcriptomics of HAdV-infected cells Anthony Petkidis
P37 Bayesian nonparametric clustering of single-cell mutational profiles Nico Borgsmüller
P38 A probabilistic model for clustering scRNAseq data Pascal Grobecker
P39 Multi-omics analysis in real time using SCfind Jimmy Tsz Hang Lee
P40 Combined unsupervised clustering and anomaly detection to identify disease associated rare cell populations Madeleine Suffiotti
P41 A network-based approach for visualization and simplification of single-cell RNA sequencing data Mariia O. Bilous
P42 rCASC: reproducible classification analysis of single cell sequencing data Raffaele Calogero
P43 Single-cell transcriptomics in unravelling the cellular diversity and molecular signature that govern anti-tumour functions of myeloid cells in vivo Marta Bica
P44 Variations on a single-cell RNAseq pipeline: benchmarks from filtering to clustering Pierre-Luc Germain
P45 Benchmarking confounder removal tools for scRNA-Seq data Ruben Chazarra - Gil
P46 Effect of rabies virus infection on expression levels of Parvalbumin and secretagogin genes in the brains of rabies infected mice Brenda Kanu
P47 Effect of rabies virus infection on the expression levels of calbindin D28k and calretinin in mouse brain George Chibuike Korie
P48 Insilico profiling and structural insights to understand impact of SNPs in pfact transporter protein by MD simulation approach Rahila Sardar
P49 Investigation of HIV transmission dynamics among young women engaged in sex work in Mombasa, Kenya Michael Becker
P50 Novel Rhabdovirus and an almost complete drain fly transcriptome recovered from two independent contaminations in clinical metagenomic samples Francisco Brito
P51 Non-invasive monitoring of drug action: exploring new assay designs for Chagas' disease in vitro drug discovery Anna Frieda Fesser
P52 Predicting tumour evolution using cancer progression models Ramon Diaz-Uriarte
P53 Genetic simulation with frequency-dependent fitness to examine the role of genetic constraints, mutator genes, and population size on cancer cooperation and competition and their effects on tumour progression Ramon Diaz-Uriarte
P54 A diversity study of the Epstein-Barr Virus (EBV) in HIV-infected patients Alexis Loetscher
P55 Discovery of a newly evolved pneumococcal Serotype 6F in Switzerland Oluwaseun Oyewole
P56 Building an automated continuous culture device to study drug resistance evolution in bacteria Eric Ulrich
P57 Static stretch affects the pro- inflammatory response of type II alveolar epithelial cells Jorge Miguel Ferreira
P58 Circulating miR-1246 in the progression of chronic obstructive pulmonary disease (COPD) in patients from the BODE cohort Sara Estefania Cazorla-Rivero
P59 Trifostigmanoside I, an active constituent from sweet potato, restores the function of MUC-2 and tight junctions through PKC & Amna Parveen
P60 Role of NLRP3 inflammasome in sterile cardiovascular disease Fumitake Kawanishi
P61 Integrating variant frequencies in neXtProt for a better representation of the human proteome Alain Gateau
P62 Genetic diversity of Mycobacterium tuberculosis from extensively drug-resistant patients from Georgia Tatjana Meyer
P63 Transcriptome analysis describing immunity and metabolism genes in peripheral blood mononuclear cells of cervical cancer patients to Senegal Moussa Ndiaye
P64 Identifying genetic modifiers of prion disease Jiang-An Yin
P65 An enhanced workflow for variant interpretation in UniProtKB/Swiss-Prot improves consistency and reuse in ClinVar Anne Estreicher
P66 CD34+ cells in liver with myogenic potential Bipasha Bose
P67 Possible therapeutic roles of diet-regulated gene expressions during brain aging using zebrafish Begün Erbaba
P68 A novel approach in stem cell therapy for alzheimer's animal model Mehdi Mehdizadeh
P69 Development of the multiscale model of germinal center B cell differentiation Bhavesh Soni
P70 Suppression of 1-deoxydihydroceramide production protects against protein aggregation and anoxia injury J. Thomas Hannich
P71 A service for the automated creation of genome-scale metabolic network model from a microbial genome Sébastien Moretti
P72 BioModels parameters: a resource to search and access parameters from published systems models Rahuman S Malik Sheriff
P73 An in-silico approach to explore the evolutionary signatures of host pathogen interactions Aranyak Goswami
P74 Major improvements in the reconciliation of metabolites and biochemical reactions to ease metabolic network reconstruction Sébastien Moretti
P75 Discovery, estimation and prediction analysis using a Bayesian survival model for complex diseases Sven Erik Ojavee
P76 In silico approach of jack bean as DPP1V inhibitory activity Andriati Ningrum
P77 In silico approach of collagen from tuna fish by-product as ACE inhibitor Andriati Ningrum
P78 Diagnostics and correction of batch effects in large-scale proteomics studies Chloe H. Lee
P79 Homopolymers in Mycobacterium tuberculosis: a source for rapid adaptation? Michaela Zwyer
P80 Assessing cancer heterogeneity among cancer types Paula Carrio Cordo
P81 Facilitating collection of literature for personalized cancer treatments Emilie Pasche
P82 Identification of potential inhibitors targeting cholinesterase: an in silico and in vitro approach Manish Kumar Tripathi
P83 Unconventional cell cycle modeling: a vision from third angle Mustafa Pasha
P84 A machine learning based algorithm for deciphering complex chemical structures of secondary metabolites by genome mining Priyesh Prateek Agrawal
P85 Hierarchical ensemble methods for ontology-based predictions in computational biology and precision medicine Marco Notaro
P86 A pipeline for characterization of possible ncRNA homologs in BLAST output Marek Schwarz
P87 Haplotype based expression quantitative Trait Loci mapping Robin Hofmeister
P88 Molecular basis of gene regulatory variation in human adipose stromal cells Daniel Alpern
P89 Protein-wide simulations to drive the design of new therapies from multi-omics data Attila Csikász-Nagy
P90 Integrating expression data into metabolome-wide GWAS identifies genes involved in the modulation of the metabolite concentration Reyhan Sonmez Flitman
P91 Remote and local services to search and visualize reactions and metabolites from the Rhea databases Parit Bansal
P92 Identifying a good animal model for age-related muscle loss in humans Anastasiya Börsch
P93 Cancer cell lines in focus: somatic copy number variation and germline variation Qingyao Huang
P94 Rhea, an expert curated resource of biochemical reactions with SPARQL endpoint Alan Bridge
P95 Representing the human metabolome in UniProtKB using Rhea Lionel Breuza
P96 A novel MASP1 gene mutation causes 3MC1 syndrome in the first reported Egyptian family AmiraA Nabil Khalaf
P97 Transcriptional regulators which are induced in HCC affect deregulation of central catabolism Sujin Park
P98 Role of mTOR in regulating DLK1-DIO3 cluster miRNAs Dritan Liko
P99 ER and mitochondrial stress in liver cancer cells Amandine Thomas
P100 Conditional estimation of the contribution of genomic regions and functional annotations to common complex disease Marion Patxot
P101 An evolutionarily conserved mechanism of translation regulation by TORC1 Sunil Shetty
P102 Interactome profiling of mTOR signalling Wenxiang Fu
P103 Role of the transcription factor TCF3 in HCC progression Stefania Battaglioni
P104 CRUNCH: completely automated analysis of ChIP-seq data Mikhail Pachkov
P105 Deciphering the landscape of phosphorylated HLA-I ligands Marthe Solleder
P106 Inferring RNA-binding sites, motifs and regulation from CLIP data with RCRUNCH Maria Katsantoni
P107 PolyASite 2.0: a comprehensive atlas of RNA 3' ends Christina Janina Herrmann
P108 ViraMiner: deep learning for identifying viral genomes in human samples Zurab Bzhalava
P109 Crunch-mara: modeling gene regulation on DNA Level Anne Krämer
P110 Protein histidine phosphorylation - a novel target in cancer therapy? Markus Linder
P111 A deep learning framework to score cancer cell proliferation and oncolytic virus efficacy in 3D tumor models Fanny Georgi
P112 sparql.uniprot.org: moving past search for research Jerven Bolleman
P113 Bionotator and NRPro: bioinformatics tools for the study of nonribosomal peptides Emma Ricart Altimiras
P114 ReSequenceR: simulating more realistic high-throughput sequencing data Stephan Schmeing
P115 UniLectin, a knowledge-base of carbohydrate-binding proteins François Bonnardel
P116 Swiss-PO. A new web tool to help predicting mutation pathogenicity for precision oncology Fanny Krebs
P117 Supporting structure prediction method development with continuous automated model eEvaluatiOn (CAMEO) Juergen Haas
P118 Studies on the interaction of rotavirus non-structural proteins NSP5, NSP2 with host cellular factors and their role in virus replication Varsha Tandra
P119 Minimisation of surface energy drives apical epithelial organisation and gives rise to Lewis' law Marco Kokic
P120 & Soumik Ray
P121 & Don Benjamin
P122 Kinetic analysis of the minimal model to describe metabolic oscillations in Bacillus subtilis biofilms Ravindra Garde
P123 Optimised nitrogen fixing bacteria: a whole cell modelling approach Leanne Massie
P124 Biomedical big data analysis and management on secure research platforms Michal Okoniewski
P125 Design and development of potential acetylcholinesterase and BACE-1 inhibitors for the treatment of Alzheimer's disease Avanish Tripathi
P126 HLA-I 9-mer peptides exhibit a preference for helical topologies in the source proteins1 Marta A. S. Perez
P127 SWISS-MODEL: homology modelling of protein structures and complexes Gerardo Tauriello
P128 Minimum error calibration and normalization for copy number analysis Bo Gao
P129 User experience (UX) at the SIB swiss institute of bioinformatics Chiara Gabella
P130 Kinetic properties of rhodanese from African locust bean seeds (Parkia biglobosa) Leonard Ehigie
P131 Genome-wide association study in Japanese cohort identifies variants near amylase genes associated with serum amylase level Zannatun Nayema
P132 Computational exploration to design and synthesise N-benzylpiperidines as multifunctional therapeutics to treat Alzheimer's disease Piyoosh Sharma
P133 Complete genome sequencing and molecular characterization of a rabies virus isolated from trade dogs in Plateau State, Nigeria Grace Kia
P134 Krini: data analysis in the cloud Alexander Kanitz
P135 Fruit of Lycium barbarum displays neurotrophic, neuritogeneis and anti-neuroinflammatory activities In-vitro Zahra Khan
P136 SWITCH edu-ID based login into SSH servers Heinz Stockinger
P137 Sodium fluoride induced skeletal muscle changes: muscle hypertrophy versus muscle atrophy and signaling mechanisms Sudheer Shenoy P
P138 Searching for robust Turing patterns using discrete models Thomas Leyshon
P139 Identification of novel microbial P450s as drug-metabolizing enzymes Lisa Marie Schmitz
P140 Nrf2/KEAP1 reporter human 3D epidermal model Bruno Guy Henri Filippi
P141 In-silico protein-wide models predicts effect of Metformin in murine liver cells Simone Rizzetto
P142 Lamin A/C promotes DNA base excision repair Scott Maynard
P143 Nsun5 in ribosome function and mammalian healthy lifespan Lisa Liendl
P144 Discovery of MYST1 small-molecule inhibitors as epigenetic tools of gene regulation Anastasiia Gryniukova
P145 Development of a ROR& Huiping Huang
P146 XFEL-based serial femtosecond crystallography in drug discovery Alexey Mishin
P147 From a new premature aging disorder towards aging mechanisms Daniela Bakula
P149 Leveraging NAD+ signalling as a treatment pathway for age-related metabolic dysfunction Brenna Osborne
P150 Targeting aging with deep learned drugs Garik Mkrtchyan
P151 The Dlk1-Dio3 miRNA cluster plays a crucial role in skeletal muscle aging by targeting Smad4 KI-SUN Kwon
P152 Text mining pathology reports and machine learning for aging knowledge discovery Michael Ben Ezra
P153 An effort to build an in vitro high-throughput screening for seizure liability based on calcium oscillation of human iPS-derived dopaminergic neurons with astrocyte Sunao Hisada
P154 Engineer the DNA damage that drives senescence Guido Keijzers
P155 Recombinant expression and assay development for Ghrelin O-acyltransferase (GOAT) to support a hit discovery program based on high-throughput screening Huiping Huang
P156 Neuropathological changes in the PDAPP transgenic mouse model of Alzheimer disease Hamed Omidi
P157 A chemical language based approach for the prediction of protein - ligand binding affinity Elif Ozkirimli
P158 CNOT6 affects genome stability by regulating mismatch repair Peng Song
P159 Pharmacokinetic parameters may vary in different mice strains after a single dose of drugs Yuliia Holota
P160 Deciphering the interplay between hypoxia and DNA metabolism in aging Amanuel Teklu
P161 Ketogenic diet to delay brain aging in Cockayne syndrome Tulika Tulika
P162 Glycation extent of hemoglobin (HbA1c) might reflect biological age Urs Nydegger
P163 Deep learning of histopathology to understand age-related disease Indra Heckenbach
P164 Modelling the collective migration of neural crest cells with multi-agent reinforcement learning Koki Shimada
P165 Investigating treatment response of patients with confirmed drug-resistant tuberculosis in an HIV-1-endemic population in Western Kenya Clement Shiluli
P166 The impact of Fluoroquinolone-resistance mutations on the rates of further drug-resistance acquisition in Mycobacterium tuberculosis Rhastin A. D. Castro
P167 Flow induced dispersion analysis (FIDA) for size-based characterization of proteins and protein interactions under native conditions Morten E. Pedersen
P168 A novel tool for the treatment of peripheral demyelinating neuropathies Anna Henzi
P169 Rational design of neuroprotective antibodies against the prion protein by phage display Assunta Senatore
P170 The smart DNA-based biosensor as a new method for mRNA in vitro detection Ekaterina A Bryushkova
P172 Construction of a multiplexed CRISPRi knockdown library in mycobacteria Kristin Winkler
P173 Use of a human urothelial organoid model for pre-clinical validation of novel ultrasound-activated microbubbles in the treatment of chronic urinary tract infection Harry Horsley
P174 High throughput discovery of novel peptides with biological function Francesca Billwiller
P175 First report of novel unimolecular amylin-adrenomedullin dual agonists Lisbeth Elster
P176 Negative-regulation of gastric proton pump by N-terminal polypeptide of Sonic Hedgehog Takuto Fujii
P177 Total synthesis of Cochinmicin I and its role as potent cyclodepsipeptide endothelin antagonist Romina Schnegotzki
P178 Towards the development of inhibitors targeting CtIP function in DNA repair Nour Lydia Mozaffari
P179 Phototoxicity in live cell imaging: the evil within Hugo Moreno
P180 The pro-inflammatory mediators adenosine and hyaluronan modulate lung fibrosis and pulmonary hypertension in Combined Pulmonary Fibrosis and Emphysema (CPFE) Harry Karmouty-Quintana
P181 investigating the prevalence of anaemia in rural gambia, in relation to levels of zinc protoporphyrin, haemoglobin and haptoglobin (phenotype and genotype) Ebrima Bah
P182 HumanGEM: the generic genome-scale metabolic model of Homo sapiens Hao Wang
P183 Structure-function relationships of high-density lipoprotein in type 2 diabetes and coronary heart disease Mathias Cardner
P184 Cysteine oxidation triggers phase separation of the tumour suppressor p16INK4A Loes van Dam
P185 Epigenetic modification associated with type II interferon gamma in challenge virus standard (CVS) strain and Nigerian street rabies virus (SRV) infected mice Maryam Abdulazeez
P186 Analysis of DNA methylation patterns and epigenetic drug response of acute myeloid leukemia Ralitsa Langova
P187 Human broncho-alveolar epithelial cells from normal and diseased lungs maintain progenitor status and form organoids. Harry Karmouty Quintana