BASEL LIFE 2018

11–14 September 2018

Congress Center Basel
Switzerland

Aging and drug discovery

Wednesday 12 September 2018

10.05 – 16.45

Innovation Forums

Aging and drug discovery

Why do we age? And what can we do about it? In this symposium, a phenomenal group of thought-leaders will uncover the latest progress in aging and longevity at the molecular, cellular and organismal level. A panel of world leading experts will give us their cutting edge reports on the latest progress in our quest to extend our healthy lifespan. We will hear from both academic and top investors on where and how commercialization of aging and longevity research will likely occur. Please join us in this merger of driven scientists and global visionaries in an event that may shape the field in years to come.

Chairs:
Alex Zhavoronkov (InSilico Medicine, Baltimore, United States)
Morten Scheibye-Knudsen (Danish Center for Aging Research/National Institute on Aging, Copenhagen, Denmark)

10.05
Welcome to the intersection of AI, longevity and drug discovery
Alex Zhavoronkov (InSilico Medicine, Baltimore, United States)
Morten Scheibye-Knudsen (Danish Center for Aging Research/National Institute on Aging, Copenhagen, Denmark)

10.15
Commercializing the science of aging biology
S.J. Olshansky
University of Illinois at Chicago and Lapetus Solutions, Chicago, IL, United States

10.35
Redox-regulation of lifespan and metbaolism
Michael Ristow (ETH Zurich, Switzerland)

10.55
Multi-stage longevity therapeutics to fight aging at every level
I.V. Ozerov, M. Bozdaganyan, A. Zhavoronkov
Insilico Medicine Inc, Pharma.AI, Insilico Medicine, Baltimore, MD, MD, United States

11.45
Systems biology of lifespan control and i'ts applications
Vadim Gladyshev (Harvard, Cambridge, United States)

12.05
Juvenescence: Investing in Longevity
Alexander Pickett (Boston, United States)

12.25
Fucoxanthin from the point of criteria of geroprotector
A. Moskalev1, M. Shaposhnikov1, Z. Guvatova2, A. Snezhkina2, A. Kudryavtseva2
1Institute of Biology of Russian Academy of Sciences, Syktyvkar, 2Engelhardt Institute of Molecular Biology of Russian Academy of Sciences, Moscow, Russian Federation

14.15
Understanding the role of Cockayne syndrome proteins in DNA repair, transcription, and accelerated aging
Martijn Luijsterburg (LUMC, Leiden, Netherlands)

14.35
Exploring the phenotypical landscape of aging
M. Scheibye-Knudsen
Center for Healthy Aging, University of Copenhagen, Copenhagen N, Denmark

14.55
Environment and skin aging – new insights and anti-aging strategies
Olga Kovalchuck (University of Lethbridge, Canada)

15.45
Quantifying and manipulating mammalian NAD synthesis
Joseph Baur (University of Pennsylvania, Philadelphia, United States)

16.05
Anti-aging drugs: what do we need now?
Judith Campisi (Buck Institute for Research on Aging, Novato, United States)

16.25
Panel discussion
Alex Zhavoronkov (InSilico Medicine, Baltimore, United States)
Polina Mamoshina (Pharma Al, Insilico Medicine, Baltimore, United States)
Dmitry Kaminskiy (Deep Knowledge Ventures, London, United Kingdom)
Michael Antonov (Oculus, San Francisco, United States)
Morten Scheibye-Knudsen (Danish Center for Aging Research/National Institute on Aging, Copenhagen, Denmark)

Kairo 1-2

Thursday 13 September 2018

10.15 – 12.45

Innovation Forums

Aging and drug discovery

Why do we age? And what can we do about it? In this symposium, a phenomenal group of thought-leaders will uncover the latest progress in aging and longevity at the molecular, cellular and organismal level. A panel of world leading experts will give us their cutting edge reports on the latest progress in our quest to extend our healthy lifespan. We will hear from both academic and top investors on where and how commercialization of aging and longevity research will likely occur. Please join us in this merger of driven scientists and global visionaries in an event that may shape the field in years to come.

Chairs:
Alex Zhavoronkov (InSilico Medicine, Baltimore, United States)
Morten Scheibye-Knudsen (Danish Center for Aging Research/National Institute on Aging, Copenhagen, Denmark)

10.15
Identifying the multidimensional regulators of aging
Stuart Maudsley (VIB University of Antwerp, Antwerp, Belgium)

10.35
Transcriptomic signature of longevity
Collin Ewald (ETH Zurich, Zurich, Switzerland)

10.55
Deep learning algorithms for DNA repair stimulators
G. Mkrtchyan1, M. Volosnikova2, A. Olesen1, A. Veviorskiy2, I. Ozerov2, D. Bakula1, A. Aliper2, G. Keijzers1, A. Zhavoronkov2, M. Scheibye-Knudsen1
1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark, 2Insilico Medicine, Inc., Johns Hopkins University, Rockville, MD, United States

11.45
The thyroid hormone axis in healthspan and lifespan
A. Martín-Montalvo
CABIMER, Seville, Spain

12.05
Promoting healthy aging through the reduction of specific dietary macronutrients
Dudley Lamming (university of Wisconsin, United States)

12.25
Сomputer vision for skin aging biomarkers investigation
Anastasia Georgievskaya (Youth Laboratories, Moscow, Russian Federation)

Kairo 1-2

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