BASEL LIFE 2018

11–14 September 2018

Congress Center Basel
Switzerland

Medicinal chemistry

Wednesday 12 September 2018

10.15 – 12.45

Innovation Forums

Medicinal chemistry

The perpetual task of Medicinal Chemistry and Drug Discovery is the finding and profiling of pharmacologically active and safe medicine.
In this forum the importance of new methodologies for profiling and synthesis of new compounds will be presented and discussed including new computational approaches for compound design.

Chairs:
Daniel Gygax (FHNW, Muttenz, Switzerland)
Gerhard Grundler (FHNW, Muttenz, Switzerland)

10.15
Fishing for compound targets using CRISPR-mediated bar-coded deletion collections
D. Estoppey1, C.M. Lee2, M. Janoschke3, M. Spiess3, G. Bonamy2, D. Hoepfner1
1Chemical Biology & Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland, 2Novartis Institutes for Tropical Diseases, Singapore, Singapore, 3Biozentrum der Universität Basel, Basel, Switzerland

10.45
Phage display selection of chemically cyclized peptides for the development of therapeutics
C. Heinis
Institute of Chemical Sciences and Engineering, EPFL, Lausanne, Switzerland

11.45
The Screening Compound Collection: a key asset for drug discovery
C. Boss
DD Chemistry Oncology, Idorsia Pharmaceuticals Ltd, Allschwil / BL, Switzerland

12.15
Can a computer design a drug?
J.G. Cumming
F. Hoffmann-La Roche, Basel, Switzerland

Shanghai 1

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